2-Methyl-8-nitroquinoline → 2-Methyl-8-aminoquinoline

Beteiligte Stoffe

Reaktionsschritte

Palladium on carbon (10%, 50 mg) was added to a solution of 2-methyl-8-nitroquinoline (500 mg, 2.66 mmol) in EtOH (40 ml) and the mixture was stirred under an atmosphere of hydrogen for 2 h. The mixture was diluted with MeOH (40 ml), filtered through celite and the filtrate was concentrated in vacuo to give the title compound (417 mg, 99%).

Herkunft & Nachweise