Glycerol → HCID 68183092, Verbindung

Reaktionsgleichung

[Cl:1][C:2]1[C:3]([CH3:12])=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([CH:8]=1)[NH2:7].O[CH2:14][CH:15]([CH2:17]O)O.[Na+].[N+](C1C=C(S([O-])(=O)=O)C=CC=1)([O-])=O.OS(O)(=O)=O.O>>[Cl:1][C:2]1[C:3]([CH3:12])=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]2[C:8]=1[CH:14]=[CH:15][CH:17]=[N:7]2

Komponenten

Edukt 4

HCID 753Glycerol

HCID 31389Sodium 3-nitrobenzenesulfonate

HCID 2516815-Chloro-4-methyl-2-nitroaniline

HCID 21910475Sulfuric acid hydrate (1:1)

Produkt 1

HCID 68183092HCID 68183092, VerbindungAusbeute 30 %

Versuchsvorschrift

In a similar fashion using route 10 general procedure 20, 5-chloro-4-methyl-2-nitroaniline (1.0 g, 5.3 mmol), glycerol (1.52 g, 16.6 mmol), 3-nitrobenzensulfonic acid sodium salt (1.55 g, 6.8 mmol) and H2SO4/H2O (6 ml, 7:5) gave the title compound (350 mg, 30%) which was used in the next step without purification.