HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyridine → Pyridine-3-sulfonic acid quinolin-8-ylamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyridine | HCID 1049 | — |
| Edukt | 8-Aminoquinoline | HCID 11359 | — |
| Edukt | Pyridine-3-sulfonyl chloride hydrochloride | HCID 12571517 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Pyridine-3-sulfonic acid quinolin-8-ylamide | HCID 25038243 | 18% |
Reaktionsschritte
In a similar fashion using route 14 general procedure 26, pyridine-3-sulfonyl chloride hydrochloride (0.30 g, 1.39 mmol), 8-aminoquinoline (0.20 g, 1.39 mmol) in pyridine (0.56 ml, 6.94 mmol) gave the title compound (70 mg, 18%) after trituration from MeOH.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09102688B2 |
| Quelldatensatz | uspto-grants-2015_08 |
| ORD ID | ord-b6cb56d4da1047a8a54bcc20d9cc94d3 |
| Quellennotiz | uspto-grants-2015_08 |