4-Chloro-8-nitroquinazoline → HCID 11462514, Verbindung

Beteiligte Stoffe

Reaktionsschritte

p-Toluene sulphonyl hydrazine hydrate (390 mg, 2.1 mmol) was added to a solution of 4-chloro-8-nitro-quinazoline 477 (400 mg, 1.91 mmol) in DCM at (10 ml) and the mixture was stirred at room temperature for 24 h. The mixture was concentrated in vacuo and washed with Et20 to give the title compound (650 mg, 95%).

Herkunft & Nachweise