Chloroform → HCID 68190303, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3]([C:5]1[CH:22]=[C:21]2[C:8]([S:9](=[O:24])(=[O:23])[NH:10][C:11]3[C:20]2=[CH:19][CH:18]=[C:17]2[C:12]=3[N:13]=[CH:14][CH:15]=[CH:16]2)=[CH:7][CH:6]=1)=[O:4].C(Cl)(Cl)[Cl:26]>>[CH3:1][O:2][C:3]([C:5]1[CH:22]=[C:21]2[C:8]([S:9](=[O:24])(=[O:23])[NH:10][C:11]3[C:20]2=[CH:19][C:18]([Cl:26])=[C:17]2[C:12]=3[N:13]=[CH:14][CH:15]=[CH:16]2)=[CH:7][CH:6]=1)=[O:4]Komponenten
3
Versuchsvorschrift
In a similar fashion using route 51 general procedure 117,6,6-dioxo-5,6-dihydro-6λ*6*-thia-4,5-diaza-chrysene-9-carboxylic acid methyl ester 307 (1.1 g, 3.2 mmol), 1,3-dichloro-5,5-dimethylhydantion (765 mg, 3.8 mmol) in chloroform (40 ml), gave the title compound (1.6 g, 57%) after washing with MeOH/DCM.
Quellen und Nachweise
- ORD-Eintrag
- ord-214ad4ee1e3348788a501928d0728c0f
- Quelldatensatz
- uspto-grants-2015_08