HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,4-Dichlorobenzyl alcohol → 2-[5-[(2,4-Dichlorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,4-Dichlorobenzyl alcohol | HCID 15684 | — |
| Edukt | HCID 178510213 | HCID 178510213 | — |
| Produkt | 2-[5-[(2,4-Dichlorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carbonitrile | HCID 86725553 | — |
Reaktionsschritte
The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and (2,4-dichlorophenyl)methanol according to the procedure for the preparation of Example 39, part C. 1H NMR (400 MHz, CDCl3): δ 5.29 (2H, s), 5.79 (1H, d, J=1.6 Hz), 7.29-7.32 (1H, m), 7.42 (1H, dd, J=1.2, 5.2 Hz), 7.45 (1H, d, J=2.4 Hz), 7.53 (1H, d, J=8.4 Hz), 7.59 (1H, d, J=1.6 Hz), 8.06 (1H, s), 8.71 (1H, d, J=4.8 Hz). [M+H] Calc'd for C16H10C12N4O, 345. Found, 345.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09107916B2 |
| Quelldatensatz | uspto-grants-2015_08 |
| ORD ID | ord-5a192074959449909418239f80240787 |
| Quellennotiz | uspto-grants-2015_08 |