Hydrochloric Acid → 3-[(Propan-2-ylsulfonyl)methyl]anilinium chloride

HRID 514704Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 514704
[CH3:1][CH:2]([S:4]([CH2:7][C:8]1[CH:9]=[C:10]([NH:14]C(=O)C)[CH:11]=[CH:12][CH:13]=1)(=[O:6])=[O:5])[CH3:3].[ClH:18].C(O)C.C(OCC)(=O)C>C(O)C>[Cl-:18].[CH3:3][CH:2]([S:4]([CH2:7][C:8]1[CH:9]=[C:10]([CH:11]=[CH:12][CH:13]=1)[NH3+:14])(=[O:6])=[O:5])[CH3:1]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 21584252Ethanol ethylacetateHCID 70976422N-{3-[(Propan-2-ylsulfonyl)methyl]phenyl}acetamide

Produkt 1

HCID 867296113-[(Propan-2-ylsulfonyl)methyl]anilinium chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of N-{3-[(propan-2-ylsulfonyl)methyl]phenyl}acetamide (5.4 g) in ethanol (29.6 mL) was treated with concentrated hydrochloric acid (35.5 mL) and refluxed for 24 hours. The reaction mixture was condensed to dryness. The title compound (3.5 g) was obtained by crystallization from ethanol/ethyl acetate.

Aufarbeitung

  1. temperaturerefluxed for 24 hours
  2. customcondensed to dryness

Quellen und Nachweise

ORD-Eintrag
ord-dea0212918ad4166a6a1d503b0117750
Quelldatensatz
uspto-grants-2015_08
Patentnummer
US09108926B2

Notizen zur Reaktion

Wird geladen…