3-Phenoxytoluene → 1-Bromo-2-methyl-4-phenoxybenzene

HRID 51535

Reaktionsgleichung

Reaktionsgleichung von HRID 51535
[O:1]([C:8]1[CH:9]=[C:10]([CH3:14])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:15]N1C(=O)CCC1=O>C(#N)C>[C:2]1([O:1][C:8]2[CH:13]=[CH:12][C:11]([Br:15])=[C:10]([CH3:14])[CH:9]=2)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 2

HCID 191653-PhenoxytolueneHCID 67184N-bromobutanimide

Produkt 1

HCID 128585521-Bromo-2-methyl-4-phenoxybenzeneAusbeute 97,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

A mixture of 3-phenoxytoluene (2.5 g, 0.0136 mol) and N-bromosuccinimide (2.54 g, 0.0142 mol) was stirred in acetonitrile (20 mL) for 2.5 hours under an atmosphere of nitrogen. The solvent was removed under reduced pressure. Carbon tetrachloride was added to the residue and the resulting solid was removed by filtration. The filtrate was concentrated to yield 4-bromo-3-methylphenyl phenyl ether as yellow oil (3.5 g, 0.0133 mol):

Aufarbeitung

  1. customThe solvent was removed under reduced pressure
  2. additionCarbon tetrachloride was added to the residue
  3. customthe resulting solid was removed by filtration
  4. concentrationThe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-41372e57b62d4ee7b9f74314c3d1de09
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06713474B2

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