(4-Bromophenoxy)(tert-butyl)dimethylsilane → 5-[(4-{[tert-Butyl(dimethyl)silyl]oxy}phenyl)amino]-1-methyl-1H-pyrazole-3-carbonitrile
Reaktionsgleichung
Br[C:2]1[CH:15]=[CH:14][C:5]([O:6][Si:7]([C:10]([CH3:13])([CH3:12])[CH3:11])([CH3:9])[CH3:8])=[CH:4][CH:3]=1.[Si](OC1C=CC(N)=CC=1)(C(C)(C)C)(C)C.[NH2:31][C:32]1[N:36]([CH3:37])[N:35]=[C:34]([C:38]#[N:39])[CH:33]=1>>[Si:7]([O:6][C:5]1[CH:14]=[CH:15][C:2]([NH:31][C:32]2[N:36]([CH3:37])[N:35]=[C:34]([C:38]#[N:39])[CH:33]=2)=[CH:3][CH:4]=1)([C:10]([CH3:13])([CH3:12])[CH3:11])([CH3:9])[CH3:8]Komponenten
4
Versuchsvorschrift
The procedure is in accordance with the protocol of Step B of Preparation 1″, replacing the 4-bromo-1-methyl-1H-pyrazole by (4-bromophenoxy)-(tert-butyl)dimethyl-silane and the 4-{[tert-butyl(dimethyl)silyl]oxy}aniline by the compound from Step A.