Hydrochloric Acid → 4-(10-Allyloxydecyloxy)benzoic acid

HRID 5163

Reaktionsgleichung

[CH2:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]I)[CH:2]=[CH2:3].C[O:17][C:18]([C:20]1[CH:21]=[CH:22][C:23]([OH:26])=[CH:24][CH:25]=1)=[O:19].C(=O)([O-])[O-].[K+].[K+].[OH-].[K+].Cl>C(O)C>[CH2:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][O:26][C:23]1[CH:24]=[CH:25][C:20]([C:18]([OH:19])=[O:17])=[CH:21][CH:22]=1)[CH:2]=[CH2:3]

Komponenten

Reaktionsbedingungen

Temperatur: 80 °C

Versuchsvorschrift

70 mmol (22.7 g) of 10-iododecyl allyl ether, 70 mmol (10.6 g) of methyl p-hydroxybenzoate, and 70 mmol (9.6 g) of potassium carbonate were refluxed in absolute ethanol for 15 hours. After addition of an aqueous potassium hydroxide solution (containing 4.0 g of potassium hydroxide) into the reaction solution, the resulting mixture was further heated at 80° C. for 5 hours. After conclusion of the reaction, the reaction solution was acidified with hydrochloric acid, and the acidified reaction solution was then concentrated under reduced pressure. Water was added to the residue to form a suspension, and the insoluble matter was collected and was then dried, to obtain 18.7 g of 4-(10-allyloxydecyloxy)benzoic acid (Yield: 80%).

Aufarbeitung

customAfter conclusion of the reaction
customthe acidified reaction solution
concentrationwas then concentrated under reduced pressure
additionWater was added to the residue
customto form a suspension
customthe insoluble matter was collected
customwas then dried

Quellen und Nachweise

ORD-Eintrag: ord-259cdfd8194a46da8519bc2b1b2c0ec8
Quelldatensatz: uspto-grants-1993_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05243065

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