Hydrazine, 1-naphthalenyl- → 3-(4-Bromo-phenyl)-1,5-di-naphthalen-1-yl-1H-[1,2,4]triazole

HRID 516496

Reaktionsgleichung

Reaktionsgleichung von HRID 516496
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[N:12][C:13]([C:15]2[C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[CH:18]=[CH:17][CH:16]=2)=O)OCC)=[CH:4][CH:3]=1.[C:25]1([NH:35][NH2:36])[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:28]=[CH:27][CH:26]=1>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]=[C:13]([C:15]3[C:24]4[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=4)[CH:18]=[CH:17][CH:16]=3)[N:35]([C:25]3[C:34]4[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=4)[CH:28]=[CH:27][CH:26]=3)[N:36]=2)=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 75240Hydrazine, 1-naphthalenyl-HCID 57610336Naphthalene-1-carboxylic acid 1-(4-bromo-phenyl)-1-ethoxy-methylideneamide

Produkt 1

HCID 576103533-(4-Bromo-phenyl)-1,5-di-naphthalen-1-yl-1H-[1,2,4]triazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel

Reaktionsbedingungen

Temperatur
25 °C

Versuchsvorschrift

The compound obtained in step A) (1.0 g, 0.026 mol) and 1-naphthyl hydrazine (0.45 g, 0.028 mol) is dissolved in CCl4 (15 ml) and stirred for 10 hours at 25° C. under a nitrogen atmosphere. The reaction mixture is stirred for 12 hours and filtered to remove traces of insoluble particles. The CCl4 solution is then concentrated and a few drops of methanol are added to the residue, wherein a brownish solid is obtained (Yield=0.7 g (56%)).

Aufarbeitung

  1. stirringThe reaction mixture is stirred for 12 hours
  2. filtrationfiltered
  3. customto remove traces of insoluble particles
  4. concentrationThe CCl4 solution is then concentrated
  5. additiona few drops of methanol are added to the residue, wherein a brownish solid
  6. customis obtained (Yield=0.7 g (56%))

Quellen und Nachweise

ORD-Eintrag
ord-d7c2db3732134b1683088925a9ff0fc8
Quelldatensatz
uspto-grants-2015_08
Patentnummer
US09113536B2

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