Potassium Carbonate → 5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Potassium Carbonate	HCID 11430	—
Edukt	2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate	HCID 2776019	—
Edukt	Methyl 5-hydroxypyridine-2-carboxylate	HCID 4715126	—
Produkt	5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester	HCID 57475878	—

Reaktionsschritte

In a manner analogous to that described in example 24 a), the alkylation of the 5-hydroxy-pyridine-2-carboxylic acid methyl ester with potassium carbonate and trifluoro-methanesulphonic acid 2,2,3,3,3-pentafluoropropyl ester yielded the 5-(2,2,3,3,3-pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester as a light yellow oil. MS (ISP): m/z=285 [M]+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09115098B2
Quelldatensatz	uspto-grants-2015_08
ORD ID	ord-40b10e743e474a6b9505fdf91121d675
Quellennotiz	uspto-grants-2015_08