Trifluoroacetic acid → (2E)-3-[5-(4-amidinophenoxycarbonyl)-thiophen-2-yl]-2-methylpropenoic acid trifluoroacetic acid salt
Reaktionsgleichung
C([O:5][C:6](=[O:27])[C:7]([CH3:26])=[CH:8][C:9]1[S:10][C:11]([C:14]([O:16][C:17]2[CH:22]=[CH:21][C:20]([C:23](=[NH:25])[NH2:24])=[CH:19][CH:18]=2)=[O:15])=[CH:12][CH:13]=1)(C)(C)C.[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31]>>[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31].[C:23]([C:20]1[CH:21]=[CH:22][C:17]([O:16][C:14]([C:11]2[S:10][C:9](/[CH:8]=[C:7](\[CH3:26])/[C:6]([OH:27])=[O:5])=[CH:13][CH:12]=2)=[O:15])=[CH:18][CH:19]=1)(=[NH:24])[NH2:25]Komponenten
3
Versuchsvorschrift
To 3-[5-(4-amidinophenoxycarbonyl)thiophen-2-yl]-2-methylpropenoic acid tert-butyl ester (0.63 g) was added trifluoroacetic acid (5 mL), and the mixture was stirred for 30 minutes. The solvent was evaporated to give the title compound (0.62 g).
Aufarbeitung
- customThe solvent was evaporated