Sulfuric Acid → 1H-Indole-2,3-dione, 6-bromo-

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To the concentrated sulfuric acid (275 mL) at 50° C. was added N-(3-Bromo-phenyl)-2-hydroxyimino-acetamide (55 g, 0.2272 mol). The temperature was raised to 90° C. and maintained for 3 h. The reaction mixture was added to ice cold water to get yellow precipitate. The precipitate was filtered and dried to get the title compound as a yellow solid [50 g, 98%]. This material was taken to the next step without any further purification.

Herkunft & Nachweise