HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanesulfonic acid → (s)-7-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-quinoline-3-carboxylic acid (1-pyridin-2-yl-propyl)-amide ethanesulfonate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanesulfonic acid | HCID 11668 | — |
| Edukt | (s)-7-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-quinoline-3-carboxylic acid (1-pyridin-2-yl-propyl)-amide | HCID 10280962 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | (s)-7-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-quinoline-3-carboxylic acid (1-pyridin-2-yl-propyl)-amide ethanesulfonate | HCID 131723182 | 102% |
Reaktionsschritte
(S)-7-[(4′-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-quinoline-3-carboxylic acid (1-pyridin-2-yl-propyl)-amide (67 mg) was dissolved in 5 ml of ethyl acetate, and ethanesulfonic acid (13 mg, 1 equivalent) was added as a solution in 1.5 ml of ethyl acetate. After 60 min, the mixture was concentrated under vacuum to afford 80 mg of the title compound as a yellow solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06713489B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-306dcd7af0f640b599433594b8b0ed1c |
| Quellennotiz | uspto-grants-2004_03 |