HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Glycerol → Apomorphine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Glycerol | HCID 753 | — |
| Edukt | 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)- | HCID 9410 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Apomorphine | HCID 6005 | — |
Reaktionsschritte
The particulate apomorphine is combined with sodium carboxymethylcellulose and glycerol. The resulting mixture is mixed thoroughly (i.e., using a vacuum mixer) and homogenized. Water is added to the mixture (with extensive mixing) to form a hydrogel containing suspended nanoparticles of apomorphine hydrochloride.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09326981B2 |
| Quelldatensatz | uspto-grants-2016_05 |
| ORD ID | ord-93ad2b7e24c4493792906455e992d7bf |
| Quellennotiz | uspto-grants-2016_05 |