1-Mercapto-2-propanol → HCID 67725881, Verbindung

HRID 52050Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 52050
[N:1]1([CH2:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]([O:14][CH2:15]/[CH:16]=[CH:17]\[CH2:18][NH:19][C:20](=[O:23])[CH2:21]Cl)[CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[SH:24][CH2:25][CH:26]([OH:28])[CH3:27]>>[N:1]1([CH2:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]([O:14][CH2:15]/[CH:16]=[CH:17]\[CH2:18][NH:19][C:20](=[O:23])[CH2:21][S:24][CH2:25][CH:26]([OH:28])[CH3:27])[CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

3

Edukt 2

HCID 1025451-Mercapto-2-propanolHCID 67725626N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-chloroacetamide

Produkt 1

HCID 67725881HCID 67725881, VerbindungAusbeute 89 %

Versuchsvorschrift

Following a procedure similar to that described in Example 1, but using N-[4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenyl]-2-chloroacetamide (prepared as described in Preparation 1) and 1-mercapto-2-propanol as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in an 89% yield.

Quellen und Nachweise

ORD-Eintrag
ord-dd8e587b9448460a96c9b6f7fe73ca5b
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05616579

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