2-Buten-1-amine, 4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-, (Z)- → HCID 178509271, Verbindung

HRID 52062

Reaktionsgleichung

Reaktionsgleichung von HRID 52062
[N:1]1([CH2:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]([O:14][CH2:15]/[CH:16]=[CH:17]\[CH2:18][NH2:19])[CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:20][C:21]1[C:25]([C:26](O)=[O:27])=[CH:24][NH:23][N:22]=1>>[NH2:20][C:21]1[C:25]([C:26]([NH:19][CH2:18]/[CH:17]=[CH:16]\[CH2:15][O:14][C:10]2[CH:9]=[C:8]([CH2:7][N:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)[CH:13]=[CH:12][N:11]=2)=[O:27])=[CH:24][NH:23][N:22]=1

Komponenten

3

Edukt 2

HCID 136724732-Buten-1-amine, 4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-, (Z)-HCID 178509273HCID 178509273, Verbindung

Produkt 1

HCID 178509271HCID 178509271, VerbindungAusbeute 38 %

Versuchsvorschrift

Following a procedure similar to that described in Example 13, but using 4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenylamine and 3-amino-4-pyrazolecarboxylic acid as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as a white powder, melting at 172°-174° C., in a 38% yield.

Quellen und Nachweise

ORD-Eintrag
ord-6eab55d75afa43558bcba0f68a663bc7
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05616579

Verknüpfte Notizen

Wird geladen…