1,4-Oxathian-2-one → N-[4-(4-Dimethylaminomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamide

HRID 52112Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 52112
[CH3:1][N:2]([CH2:4][C:5]1[CH:10]=[CH:9][N:8]=[C:7]([O:11][CH2:12]/[CH:13]=[CH:14]\[CH2:15][NH2:16])[CH:6]=1)[CH3:3].[O:17]1[CH2:22][CH2:21][S:20][CH2:19][C:18]1=[O:23]>>[CH3:1][N:2]([CH2:4][C:5]1[CH:10]=[CH:9][N:8]=[C:7]([O:11][CH2:12]/[CH:13]=[CH:14]\[CH2:15][NH:16][C:18](=[O:23])[CH2:19][S:20][CH2:21][CH2:22][OH:17])[CH:6]=1)[CH3:3]

Komponenten

3

Edukt 2

HCID 3510601,4-Oxathian-2-oneHCID 136724794-(4-Dimethylaminomethyl-2-pyridyloxy)-cis-2-butenylamine

Produkt 1

HCID 67725807N-[4-(4-Dimethylaminomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamideAusbeute 53 %

Versuchsvorschrift

Following a procedure similar to that described in Example 68, but using 4-(4-dimethylaminomethyl-2-pyridyloxy)-cis-2-butenylamine and 1,4-oxathian-2-one as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a 53% yield.

Quellen und Nachweise

ORD-Eintrag
ord-f37fbe5f088f4ce5998302782341a4c9
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05616579

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