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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 52119Erstellt: 26. Oktober 2026

Pivaloyl chloride → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-[2-(2,2-dimethylpropionyloxy)ethylthio]acetamide

https://huagongshe.com/reaction/52119

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPivaloyl chlorideHCID 62493—
EduktN-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamideHCID 67725880—
ProduktN-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-[2-(2,2-dimethylpropionyloxy)ethylthio]acetamideHCID 6772620263%

Reaktionsschritte

Following a procedure similar to that described in Example 7, but using N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamide (prepared as described in Example 1) and 2,2-dimethylpropionyl chloride as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a 63% yield.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05616579
Quelldatensatzuspto-grants-1997_04
ORD IDord-ea6367efeb134e1193e085d4a3f59fd4
Quellennotizuspto-grants-1997_04