4-Aminostyrene → 1-(4-Vinylphenyl)-3-[3,5-bis(trifluoromethyl)phenyl]thiourea

Beteiligte Stoffe

Reaktionsschritte

To a stirred solution of 4-aminostyrene (3.5 mmol) in dry THF (20 mL) under nitrogen was added 3,5-bis-(trifluoromethyl)phenyl isothiocyanate (3.5 mmol). The solution was refluxed overnight and then the solvent was evaporated under reduced pressure. The resulting solid residue was purified by column chromatography to yield the desired product in 60% yield.

Herkunft & Nachweise