Hydrochloric Acid → 3-(5H-tetrazol-5-yl)morpholine hydrochloride

HRID 524759Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 524759
[N:1]1[CH:5]([CH:6]2[CH2:11][O:10][CH2:9][CH2:8][N:7]2C(OC(C)(C)C)=O)[N:4]=[N:3][N:2]=1.[ClH:19]>CCOC(C)=O>[ClH:19].[N:4]1[CH:5]([CH:6]2[CH2:11][O:10][CH2:9][CH2:8][NH:7]2)[N:1]=[N:2][N:3]=1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 90043836Tert-butyl 3-(5H-tetrazol-5-yl)morpholine-4-carboxylate

Produkt 1

HCID 900434363-(5H-tetrazol-5-yl)morpholine hydrochlorideAusbeute 70 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

Tert-butyl 3-(5H-tetrazol-5-yl)morpholine-4-carboxylate (2 g, 7.8 mmol) was reacted with a solution of HCl in EtOAc (6 mol/L, 30 mL) according to the procedure as described in Example 18, Step B to give the title compound as a grey solid (1.05 g, 70%). The compound was characterized by the following spectroscopic data:

Quellen und Nachweise

ORD-Eintrag
ord-6e912af3ea4548d89de5bb12d015fa50
Quelldatensatz
uspto-grants-2016_05
Patentnummer
US09340538B2

Notizen zur Reaktion

Wird geladen…