5-Methoxy-1,3-thiazol-2-amine → 5-Methoxythiazole-2-carbonitrile

HRID 524802Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 524802
[CH3:1][O:2][C:3]1[S:7][C:6](N)=[N:5][CH:4]=1.[C:9]([Cu])#[N:10]>>[CH3:1][O:2][C:3]1[S:7][C:6]([C:9]#[N:10])=[N:5][CH:4]=1

Komponenten

3

Edukt 2

HCID 203162835-Methoxy-1,3-thiazol-2-amineHCID 178418546HCID 178418546, Verbindung

Produkt 1

HCID 900443835-Methoxythiazole-2-carbonitrileAusbeute 30 %

Versuchsvorschrift

5-methoxythiazol-2-amine (2.6 g, 20 mmol) was reacted with CuCN (4 g, 44 mmol) according to the procedure as described in Example 61, Step A to give the title compound as brownish oil (0.84 g, 30%). The compound was characterized by the following spectroscopic data:

Quellen und Nachweise

ORD-Eintrag
ord-b60f1450e100498aa2dcb7364c0119c2
Quelldatensatz
uspto-grants-2016_05
Patentnummer
US09340538B2

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