m-Chloroperbenzoic acid → 2-Methyl-propane-2-sulfonic acid (2-bromo-ethyl)-amide

Reaktionsgleichung

[Br:1][CH2:2][CH2:3][NH:4][S:5]([C:7]([CH3:10])([CH3:9])[CH3:8])=[O:6].C1C=C(Cl)C=C(C(OO)=[O:19])C=1>>[Br:1][CH2:2][CH2:3][NH:4][S:5]([C:7]([CH3:10])([CH3:9])[CH3:8])(=[O:19])=[O:6]

Komponenten

Edukt 2

HCID 70297m-Chloroperbenzoic acid

HCID 867137312-Methyl-propane-2-sulfinic acid (2-bromo-ethyl)-amide

Produkt 1

HCID 636888052-Methyl-propane-2-sulfonic acid (2-bromo-ethyl)-amideAusbeute 46,8 %

Reaktionsbedingungen

Temperatur: 25 °C

Versuchsvorschrift

To a solution of 2-methyl-propane-2-sulfinic acid (2-bromo-ethyl)-amide (0.8 g, 3.5 mmol) was added mCPBA (77%, 0.95 g, 4.2 mmol) and stirred at a temperature of about 25° C. for 2 hrs. The reaction mixture was condensed and purified to provide 2-methyl-propane-2-sulfonic acid (2-bromo-ethyl)-amide as a white solid (0.4 g, 46% yield).

Aufarbeitung

customcondensed
custompurified

Quellen und Nachweise

ORD-Eintrag: ord-9955dfe097094ee2be6631161f9d01e9
Quelldatensatz: uspto-grants-2016_05
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09346808B2

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