HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
8-Boc-3,8-diaza-bicyclo(3.2.1)octane → 3-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-3,8-diaza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 8-Boc-3,8-diaza-bicyclo(3.2.1)octane | HCID 15740908 | — |
| Edukt | tert-Butyl 4,7-diazaspiro(2.5)octane-4-carboxylate | HCID 51358567 | — |
| Edukt | 7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,7-diazaspiro[2.5]octane-4-carboxylic acid tert-butyl ester | HCID 57477280 | — |
| Produkt | 3-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-3,8-diaza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester | HCID 57477265 | — |
Reaktionsschritte
Prepared in a way similar to Intermediate 1, using 3,8-diaza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester, instead of 4,7-diaza-spiro[2.5]octane-4-carboxylic acid tert-butyl ester.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09346809B2 |
| Quelldatensatz | uspto-grants-2016_05 |
| ORD ID | ord-480b82ed36624265aaf7d516d070a956 |
| Quellennotiz | uspto-grants-2016_05 |