Hydrochloric Acid → Hydrochloric Acid
Reaktionsgleichung
C(OC([N:8]1[CH2:11][CH:10]([C:12]2[O:13][C:14]([CH3:17])=[CH:15][N:16]=2)[CH2:9]1)=O)(C)(C)C.[ClH:18]>O1CCOCC1>[ClH:18].[NH:8]1[CH2:11][CH:10]([C:12]2[O:13][C:14]([CH3:17])=[CH:15][N:16]=2)[CH2:9]1.[ClH:18]Komponenten
5
Edukt 2
Produkt 2
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To 57 mg (0.24 mmol) 3-(5-methyl-oxazol-2-yl)-azetidine-1-carboxylic acid tert-butyl ester was added 2 mL (8 mmol) HCl in dioxane (4 M), and the reaction was stirred at room temperature for 1 hour. The solvent was evaporated to give the desired product as a HCl salt, which was used for the next step without further purification.
Aufarbeitung
- customThe solvent was evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-0f29d1d5d926482f8b6efb58f7f58d2c
- Quelldatensatz
- uspto-grants-2016_05
- Patentnummer
- US09346816B2
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