tert-Butyl Formate → Tert-butyl 5-(2-ethoxy-2-oxoethyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate
Reaktionsgleichung
[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:7]=[C:8]2[C:14]3([CH2:19][CH2:18][N:17](C(OCCCC)=O)[CH2:16][CH2:15]3)[CH:13]=[N:12][C:9]2=[CH:10][CH:11]=1)[CH3:2].[CH:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29]>>[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:7]=[C:8]2[C:14]3([CH2:19][CH2:18][N:17]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[CH2:16][CH2:15]3)[CH2:13][NH:12][C:9]2=[CH:10][CH:11]=1)[CH3:2]Komponenten
3
Versuchsvorschrift
tert-butyl 5-(2-ethoxy-2-oxoethyl)spiro[indoline-3,4′-piperidine]-1′-carboxylate was prepared by the procedures described in Example 1, Step 2, substituting tert-butyl 5-chlorospiro[indole-3,4′-piperidine]-1′-carboxylate with butyl 5-(2-ethoxy-2-oxoethyl)spiro[indole-3,4′-piperidine]-1′-carboxylate. LCMS (APCI+) m/z 275.2 [M+H−Boc]+; Rt=3.58 min.
Quellen und Nachweise
- ORD-Eintrag
- ord-0f16b993c01745e283264e850836d300