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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 52944Erstellt: 24. Oktober 2026

Glycine ethyl ester, hydrochloride → N-Ethoxycarbonylmethyl-2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-hydroxymethylimidazole-5-carboxamide

https://huagongshe.com/de/reaction/52944

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktGlycine ethyl ester, hydrochlorideHCID 2723640—
EduktSuccinimido 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-hydroxymethylimidazole-5-carboxylateHCID 19036239—
LösungsmittelTriethylamineHCID 8471—
ProduktN-Ethoxycarbonylmethyl-2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-hydroxymethylimidazole-5-carboxamideHCID 19036286—

Reaktionsschritte

Following a procedure similar to that described in Example 53, but using 0.307 g of succinimido 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-hydroxymethylimidazole-5-carboxylate [prepared as described in Example 52(a)], 89 mg of ethyl glycinate hydrochloride and 0.089 ml of triethylamine, 0.202 g of the

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05616599
Quelldatensatzuspto-grants-1997_04
ORD IDord-d8ae651d28ae461294e4f692d26523fc
Quellennotizuspto-grants-1997_04