4,4'-Dimethoxybenzil → 4,4'-Dihydroxybenzil

HRID 530417

Reaktionsgleichung

Reaktionsgleichung von HRID 530417
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([C:11]([C:13]2[CH:18]=[CH:17][C:16]([O:19]C)=[CH:15][CH:14]=2)=[O:12])=[O:10])=[CH:5][CH:4]=1>Br.CC([O-])=O>[OH:2][C:3]1[CH:4]=[CH:5][C:6]([C:9](=[O:10])[C:11]([C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=2)=[O:12])=[CH:7][CH:8]=1

Komponenten

4

Edukt 1

HCID 710434,4'-Dimethoxybenzil

Produkt 1

HCID 4582044,4'-DihydroxybenzilAusbeute 105,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 175AcetateLösungsmittelHCID 260Hydrogen BromideLösungsmittel

Versuchsvorschrift

4,4′-dimethoxybenzil (2.0 g, 7.41 mmol) was dissolved in 30 mL of hydrogen bromide and 10 mL of acetic acid glacial. The reaction was stirred at reflux temperature overnight. The mixture was extracted with ethyl acetate and the organic phase was washed with water, dried over sodium sulphate. Concentration under vaccum gave the title compound as a yellow solid (1.9 g, quantitative).

Aufarbeitung

  1. temperatureat reflux temperature overnight
  2. extractionThe mixture was extracted with ethyl acetate
  3. washthe organic phase was washed with water
  4. dry with materialdried over sodium sulphate
  5. concentrationConcentration under vaccum

Quellen und Nachweise

ORD-Eintrag
ord-4a62e416177a4f4ebd82c7f82b8a06e7
Quelldatensatz
uspto-grants-2016_05
Patentnummer
US09353089B2

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