Ethyl 4,6-dimethoxypyrimidine-2-carboxylate → 4,6-Dimethoxypyrimidin-2-carboxylic acid amide

Beteiligte Stoffe

Reaktionsschritte

Ethyl-4,6-dimethoxy-pyrimidin-2-carboxylate (25 g, 1 eq.) in NH3/MeOH (7 M, 15 mL) was irradiated in a microwave reactor at 100° C. for 15 min. The solution was concentrated in vacuo to yield compound 286 as a beige solid in 100% yield. MS (ESI, EI+): m/z=184 (MH+).

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