Sodium Carbonate → 5-(3-(1-(3,5-difluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-2-methoxy-N-methylbenzenesulfonamide

Reaktionsgleichung

FC1C=CC=CC=1CN1C=C(C2C3C(=NC=C(C4C=C(NS(C)(=O)=O)C=CC=4)C=3)NC=2)C=N1.I[C:35]1[C:43]2[C:38](=[N:39][CH:40]=[C:41]([C:44]3[CH:45]=[CH:46][C:47]([O:55][CH3:56])=[C:48]([S:50]([NH:53][CH3:54])(=[O:52])=[O:51])[CH:49]=3)[CH:42]=2)[N:37]([S:57]([C:60]2[CH:66]=[CH:65][C:63]([CH3:64])=[CH:62][CH:61]=2)(=[O:59])=[O:58])[CH:36]=1.[F:67][C:68]1[CH:69]=[C:70]([CH:88]=[C:89]([F:91])[CH:90]=1)[CH2:71][N:72]1[C:76]([CH3:77])=[C:75](B2OC(C)(C)C(C)(C)O2)[C:74]([CH3:87])=[N:73]1.C(=O)([O-])[O-].[Na+].[Na+]>C1(C)C=CC=CC=1.C(O)C.O>[F:67][C:68]1[CH:69]=[C:70]([CH:88]=[C:89]([F:91])[CH:90]=1)[CH2:71][N:72]1[C:76]([CH3:77])=[C:75]([C:35]2[C:43]3[C:38](=[N:39][CH:40]=[C:41]([C:44]4[CH:45]=[CH:46][C:47]([O:55][CH3:56])=[C:48]([S:50]([NH:53][CH3:54])(=[O:52])=[O:51])[CH:49]=4)[CH:42]=3)[N:37]([S:57]([C:60]3[CH:66]=[CH:65][C:63]([CH3:64])=[CH:62][CH:61]=3)(=[O:59])=[O:58])[CH:36]=2)[C:74]([CH3:87])=[N:73]1