3-Chloro-5-(trifluoromethyl)benzaldehyde → 3'-Bromo-5'-(trifluoromethyl)acetophenone

HRID 534848Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 534848
[Br:1][C:2]1[CH:3]=[C:4]([CH:12]([OH:14])[CH3:13])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.ClC1C=C(C=C(C(F)(F)F)C=1)C=O>>[Br:1][C:2]1[CH:3]=[C:4]([C:12](=[O:14])[CH3:13])[CH:5]=[C:6]([C:8]([F:10])([F:11])[F:9])[CH:7]=1

Komponenten

3

Edukt 2

HCID 38570333-Chloro-5-(trifluoromethyl)benzaldehydeHCID 57980200HCID 57980200, Verbindung

Produkt 1

HCID 218526683'-Bromo-5'-(trifluoromethyl)acetophenoneAusbeute 85 %

Versuchsvorschrift

The title compound was prepared from 1-(3-bromo-5-(trifluoromethyl)phenyl)ethanol (Reference Example 40) by a procedure similar to the one described for 3-chloro-5-(trifluoromethyl)benzaldehyde (Reference Example 31) to provide 1-(3-bromo-5-(trifluoromethyl)-phenyl)ethanone (17.94 g, 85%) as a pale yellow oil.

Quellen und Nachweise

ORD-Eintrag
ord-131bf99e51554856abbf9a6ee9670eaa
Quelldatensatz
uspto-grants-2014_10
Patentnummer
US08853215B2

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