Ethyl isothiocyanatoformate → 1-{[3-(2-Ethoxyethoxy)pyridin-2-yl]methyl}-2-thioxo-1,2,3,5-tetrahydro-pyrrolo[3,2-d]pyrimidin-4-one
Reaktionsgleichung
C(O[C:4]([C:6]1[NH:7][CH:8]=[CH:9][C:10]=1[NH:11][CH2:12][C:13]1[C:18]([O:19][CH2:20][CH2:21][O:22][CH2:23][CH3:24])=[CH:17][CH:16]=[CH:15][N:14]=1)=[O:5])C.C(OC([N:30]=[C:31]=[S:32])=O)C>>[CH2:23]([O:22][CH2:21][CH2:20][O:19][C:18]1[C:13]([CH2:12][N:11]2[C:10]3[CH:9]=[CH:8][NH:7][C:6]=3[C:4](=[O:5])[NH:30][C:31]2=[S:32])=[N:14][CH:15]=[CH:16][CH:17]=1)[CH3:24]Komponenten
3
Versuchsvorschrift
The title compound (0.051 g, 28%) was prepared in accordance with general method B using 3-({[3-(2-ethoxyethoxy)pyridin-2-yl]methyl}amino)-1H-pyrrole-2-carboxylic acid ethyl ester (0.17 g, 0.52 mmol) and ethoxycarbonyl isothiocyanate (0.07 mL, 0.62 mmol).