HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → Cni H1594
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 3'-Aminoacetophenone | HCID 7417 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | 2-Amino-4-chloro-6-methylpyrimidine | HCID 21810 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Cni H1594 | HCID 133110 | 78,5% |
Reaktionsschritte
Compound No. 15: A suspension of m-aminoacetophenone (2.7 g) and 2-amino-4-chloro-6-methylpyrimidine (2.87 g) in 40 mL water was treated with 1.7 mL concentrated HCl and heated at reflux for 1 hour. Addition of 40 mL 1N KOH gave a light buff solid, which was filtered out and dried to give 3.8 g 4-(3-acetylphenyl)amino-2-amino-6-methylpyrimidine, mp 196°-98° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05620983 |
| Quelldatensatz | uspto-grants-1997_04 |
| ORD ID | ord-57b6db78e12649efb92bda60463822eb |
| Quellennotiz | uspto-grants-1997_04 |