5-(Chloromethyl)pyrimidine → HCID 67960702, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:14]=[CH:13][C:12]([CH2:15][O:16][C:17]3[CH:22]=[CH:21][NH:20][C:19](=[O:23])[CH:18]=3)=[CH:11][CH:10]=2)=[CH:4][C:3]=1[C:24]([F:27])([F:26])[F:25].Cl[CH2:29][C:30]1[CH:31]=[N:32][CH:33]=[N:34][CH:35]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:14]=[CH:13][C:12]([CH2:15][O:16][C:17]3[CH:22]=[CH:21][N:20]([CH2:29][C:30]4[CH:31]=[N:32][CH:33]=[N:34][CH:35]=4)[C:19](=[O:23])[CH:18]=3)=[CH:11][CH:10]=2)=[CH:4][C:3]=1[C:24]([F:27])([F:25])[F:26]Komponenten
3
Versuchsvorschrift
The title compound was prepared by a procedure similar to that described for E21 starting from 4-{[(4-{[4-Chloro-3-(trifluoromethyl)phenyl]oxy}phenyl)methyl]oxy}-2 (1H)-pyridinone and 5-(chloromethyl)pyrimidine. LC-MS (ESI): m/z 488 [M+H]+; 3.57 min (ret time).
Aufarbeitung
- custom3.57 min (ret time)
Quellen und Nachweise
- ORD-Eintrag
- ord-6afe18422a244f9d81e49d85e178cd7d
- Quelldatensatz
- uspto-grants-2014_10