Ethylenediamine → 2-(4,5-dihydro-1H-imidazol-2-yl)-5-methoxyaniline

HRID 536234Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 536234
[NH2:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH2:12](N)[CH2:13][NH2:14]>>[NH:5]1[CH2:12][CH2:13][N:14]=[C:4]1[C:3]1[CH:6]=[CH:7][C:8]([O:10][CH3:11])=[CH:9][C:2]=1[NH2:1]

Komponenten

3

Edukt 2

HCID 3301EthylenediamineHCID 37231282-Amino-4-methoxybenzonitrile

Produkt 1

HCID 583773892-(4,5-dihydro-1H-imidazol-2-yl)-5-methoxyaniline

Versuchsvorschrift

The procedure used for the preparation of Intermediate C, Step 3 was used to prepare the title compound from 2-amino-4-methoxybenzonitrile (Step 1) and ethylene diamine. High vacuum drying gave the title compound (44 g, 92%). HPLC MS RT=1.04 min, MH+=192.

Quellen und Nachweise

ORD-Eintrag
ord-6f1f7ea4199742c8a19fd19163199517
Quelldatensatz
uspto-grants-2014_10
Patentnummer
US08859572B2

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