Ammonia → HCID 58994939, Verbindung
Reaktionsgleichung
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:16]#[N:17])[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].ClC(OC1C=C[C:25]([N+:28]([O-])=O)=CC=1)=O.N.[O:32]1CCOCC1>>[C:16]([C:10]1([C:7]2[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)[CH2:15][CH2:14][N:13]([C:25]([NH2:28])=[O:32])[CH2:12][CH2:11]1)#[N:17]Komponenten
5
Versuchsvorschrift
The title compound is prepared from 4-(4-nitro-phenyl)-piperidine-4-carbonitrile (as prepared in Example 77, step (a)) using 4-nitro-phenyl chloroformate and ammonia in 1,4-dioxane according to the procedure in QSAR & Combinatorial Science, 23(10), 854-858 (2004).