Thionyl Chloride → HCID 75058251, Verbindung

Reaktionsgleichung

[C:1]12([C:11]([OH:13])=O)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[O:2]1)[CH2:8]2.S(Cl)([Cl:16])=O>>[C:1]12([C:11]([Cl:16])=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[O:2]1)[CH2:8]2

Komponenten

Edukt 2

HCID 24386Thionyl Chloride

HCID 668516802-Oxatricyclo[3.3.1.1,3,7]decane-1-carboxylic acid

Produkt 1

HCID 75058251HCID 75058251, Verbindung

Versuchsvorschrift

A solution of Example 81B (0.1 g, 0.55 mmol) in 5 mL of thionyl chloride was warmed to reflux and stirred for 2 hours. The mixture was cooled to ambient temperature and concentrated under reduced pressure. The residue was diluted with 5 mL of toluene and concentrated under reduced pressure three times to afford the title compound, which was used without additional purification or characterization.

Aufarbeitung

temperatureto reflux
concentrationconcentrated under reduced pressure
additionThe residue was diluted with 5 mL of toluene
concentrationconcentrated under reduced pressure three times

Quellen und Nachweise

ORD-Eintrag: ord-ad8e1afd0af04c93988a88aec06ccaa5
Quelldatensatz: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08865753B2

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