Veratroyl chloride → HCID 86629951, Verbindung
Reaktionsgleichung
[CH3:1][CH:2]1[CH2:7][CH:6]([NH2:8])[CH:5]([CH:9]([CH3:11])[CH3:10])[CH2:4][CH2:3]1.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:17](Cl)=[O:18]>>[CH:9]([C@@H:5]1[CH2:4][CH2:3][C@@H:2]([CH3:1])[CH2:7][C@@H:6]1[NH:8][C:17](=[O:18])[C:16]1[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:14]([O:13][CH3:12])[CH:15]=1)([CH3:11])[CH3:10].[CH:9]([C@H:5]1[CH2:4][CH2:3][C@H:2]([CH3:1])[CH2:7][C@H:6]1[NH:8][C:17](=[O:18])[C:16]1[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:14]([O:13][CH3:12])[CH:15]=1)([CH3:11])[CH3:10]Komponenten
3
Versuchsvorschrift
The aforementioned product is obtained as a colorless solid containing in total 97.8% of the desired neomenthylamine derivatives from racemic neomenthylamine, as in the GP, by reaction with 3,4-dimethoxybenzoylchloride. Furthermore, two further isomeric menthylamine derivatives are present at 1.3% and 0.9%, corresponding to a purity over all stereoisomers of 100.0%.
Aufarbeitung
- customThe aforementioned product is obtained as a colorless solid