Hydrogen Bromide → 6-(Aminomethyl)pyridin-2(1H)-one hydrobromide

HRID 542263Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 542263
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9]C)[N:4]=1.[BrH:11]>>[BrH:11].[NH2:1][CH2:2][C:3]1[NH:4][C:5](=[O:9])[CH:6]=[CH:7][CH:8]=1

Komponenten

3

Edukt 2

HCID 260Hydrogen BromideHCID 13882973(6-Methoxypyridin-2-yl)methanamine

Produkt 1

HCID 135635896-(Aminomethyl)pyridin-2(1H)-one hydrobromide

Versuchsvorschrift

The crude product from Example 2 was combined with 10 ml of 48% hydrobromic acid, and the resulting mixture was heated at its reflux temperature for one hour. Evaporation to dryness provided 6-aminomethyl-2(1H)-pyridone hydrobromide as a water-soluble solid. The structural assignment was supported by infrared and nuclear magnetic resonance spectral analyses.

Aufarbeitung

  1. temperaturethe resulting mixture was heated at its
  2. temperaturereflux temperature for one hour
  3. customEvaporation to dryness

Quellen und Nachweise

ORD-Eintrag
ord-1a9f767402184eff825e95da8669c952
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04656285

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