Aniline → 3-(4-methoxyphenyl)-4-phenyl-5-methyl-4H-1,2,4-triazole

HRID 542871

Reaktionsgleichung

Reaktionsgleichung von HRID 542871
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.P(Cl)(Cl)Cl.[CH3:12][O:13][C:14]1[CH:26]=[CH:25][C:17]([C:18]([NH:20][NH:21][C:22](=O)[CH3:23])=O)=[CH:16][CH:15]=1>ClC1C=CC=CC=1Cl>[CH3:12][O:13][C:14]1[CH:26]=[CH:25][C:17]([C:18]2[N:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:22]([CH3:23])=[N:21][N:20]=2)=[CH:16][CH:15]=1

Komponenten

5

Edukt 3

HCID 6115AnilineHCID 24387Phosphorus trichlorideHCID 839858N'-acetyl-4-methoxybenzohydrazide

Produkt 1

HCID 130540233-(4-methoxyphenyl)-4-phenyl-5-methyl-4H-1,2,4-triazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 72391,2-DichlorobenzeneLösungsmittel

Versuchsvorschrift

Using the procedure of Step B in Example 1, 26.3 ml of aniline, 150 ml of o-dichlorobenzene, 4.65 ml of phosphorus trichloride and 10 g of N-(4-methoxybenzoyl)-N'-acetyl-hydrazine [prepared by process of J. Org., Vol. 19 (1954), p. 194-201] were reacted to obtain 7.1 g of 3-(4-methoxyphenyl)-4-phenyl-5-methyl-4H-1,2,4-triazole melting at 140°-141° C.

Aufarbeitung

  1. customwere reacted

Quellen und Nachweise

ORD-Eintrag
ord-37d150b3944448f189500d67a146a3b8
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04659729

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