5-Bromopentanenitrile → HCID 178439679, Verbindung

HRID 543222Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 543222
[OH:1][C:2]1[C:15]([CH2:16][CH2:17][CH3:18])=[C:14]([OH:19])[CH:13]=[CH:12][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5].Br[CH2:21][CH2:22][CH2:23][CH2:24][C:25]#[N:26].[NH:27]1C=N[N:29]=[N:28]1>>[C:4]([C:3]1[CH:12]=[CH:13][C:14]([O:19][CH2:21][CH2:22][CH2:23][CH2:24][C:25]2[NH:26][N:29]=[N:28][N:27]=2)=[C:15]([CH2:16][CH2:17][CH3:18])[C:2]=1[OH:1])(=[O:5])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Komponenten

4

Edukt 3

HCID 794355-BromopentanenitrileHCID 13019373(2,4-Dihydroxy-3-propylphenyl)(phenyl)methanoneHCID 178418441HCID 178418441, Verbindung

Produkt 1

HCID 178439679HCID 178439679, Verbindung

Versuchsvorschrift

The title compound was prepared by first reacting 7.68 g. of 2,4-dihydroxy-3-propylbenzophenone with 4.86 g. of 5-bromovaleronitrile according to the procedure in Example 21. The reaction afforded 8.2 g. of the nitrile intermediate of the title compound. This nitrile intermediate was then converted to the tetrazole following the procedure of Example 8 giving 1.2 g. of the title compound, m.p. about 114°-115° C.

Aufarbeitung

  1. customThe title compound was prepared
  2. customThe reaction afforded 8.2 g

Quellen und Nachweise

ORD-Eintrag
ord-02fc2c6a40c64c2a986cb49677145d01
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04661505

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