Potassium Carbonate → HCID 21294045, Verbindung

HRID 543226Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 543226
Br[CH:2]([CH2:11][CH2:12][CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8].[CH3:14][CH2:15][CH2:16][C:17]1[C:22]([OH:23])=[C:21]([C:24]([CH3:26])=[O:25])[CH:20]=[CH:19][C:18]=1[OH:27].C(=O)([O-])[O-].[K+].[K+].[OH-].[Na+]>C(O)C.CC(C)=O>[C:24]([C:21]1[CH:20]=[CH:19][C:18]([O:27][CH:2]([CH2:11][CH2:12][CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8])=[C:17]([CH2:16][CH2:15][CH3:14])[C:22]=1[OH:23])(=[O:25])[CH3:26]

Komponenten

7

Edukt 4

HCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 27751982',4'-Dihydroxy-3'-propylacetophenoneHCID 21294048HCID 21294048, Verbindung

Produkt 1

HCID 21294045HCID 21294045, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittelHCID 702EthanolLösungsmittel

Versuchsvorschrift

Following the procedures of Examples 15 E and 15F, 1.18 g. of methyl 6-bromo-nonanoate and 0.91 g. of 2,4-dihydroxy-3-propylacetophenone were reacted in the presence of 0.65 g. of potassium carbonate in 40 ml. of acetone. Hydrolysis of the ester intermediate with sodium hydroxide in aqueous ethanol gave the title product, M+ =350; NMR.

Quellen und Nachweise

ORD-Eintrag
ord-4c3ae2b8cc054269baaf62d1ca5cc75c
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04661505

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