Methyl iodide → 4-tert-Butyl-2-(methanesulfonyl)-1-methoxybenzene

HRID 543373Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 543373
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:13]([OH:15])=[O:14])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1)([CH3:4])[CH3:3].[CH2:16](N(CC)CC)C.IC>CC(C)=O>[CH3:4][C:2]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:6]=1)([CH3:1])[CH3:3]

Komponenten

5

Edukt 3

HCID 6328Methyl iodideHCID 8471TriethylamineHCID 13210234HCID 13210234, Verbindung

Produkt 1

HCID 127215654-tert-Butyl-2-(methanesulfonyl)-1-methoxybenzene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

17.4 g (0.076 mol) of 3-(1,1-dimethylethyl)-6-methoxybenzenesulfinic acid are suspended in 120 ml of acetone, and 13.3 ml (0.095 mol) of triethylamine and 8.5 ml (0.12 mol) of iodomethane are added. The mixture is stirred at room temperature for 2 hours and then poured onto ice-water. The precipitate which separates out is filtered off with suction and recrystallized from N-butanol.

Aufarbeitung

  1. additionpoured onto ice-water
  2. filtrationThe precipitate which separates out is filtered off with suction
  3. customrecrystallized from N-butanol

Quellen und Nachweise

ORD-Eintrag
ord-7fa0fd4a64fa42e292b09e0f1c4eef59
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04661636

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