Methanol → HCID 13423729, Verbindung

HRID 543380Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 543380
[C:1]([C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[C:6]([S:14]([CH3:17])(=[O:16])=[O:15])[C:5]=1[OH:18])([OH:3])=[O:2].S(=O)(=O)(O)O.[CH3:24]O>>[CH3:24][O:2][C:1]([C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[C:6]([S:14]([CH3:17])(=[O:16])=[O:15])[C:5]=1[OH:18])=[O:3]

Komponenten

4

Edukt 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 13423728HCID 13423728, Verbindung

Produkt 1

HCID 13423729HCID 13423729, Verbindung

Versuchsvorschrift

1.0 g (0.003 mol) of 2-carboxy-4-(1,1-dimethylethyl)-6-methylsulfonylphenol prepared in Example 3 is dissolved in 6 ml of methanol, and heated under reflux with 0.1 ml of concentrated sulfuric acid for 2 days. The mixture is poured onto ice-water, and this is extracted with ethyl acetate, the solvent is removed in vacuo and the residue is subjected to chromatography on silica gel using ethyl acetate/toluene 4:1 as the eluting agent.

Aufarbeitung

  1. temperatureheated
  2. additionThe mixture is poured onto ice-water
  3. extractionthis is extracted with ethyl acetate
  4. customthe solvent is removed in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-c15f472ec7f346ed9c3ce48356232004
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04661636

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