Ethyl bromopyruvate → HCID 178470113, Verbindung

HRID 545105

Reaktionsgleichung

Reaktionsgleichung von HRID 545105
Br[CH2:2][C:3](=O)[C:4]([O:6][CH2:7][CH3:8])=[O:5].[C:10](=[S:13])([S-:12])[NH2:11].[NH4+]>C(O)C>[CH2:7]([O:6][C:4]([C:3]1[N:11]=[C:10]([SH:13])[S:12][CH:2]=1)=[O:5])[CH3:8]

Komponenten

4

Edukt 2

HCID 66144Ethyl bromopyruvateHCID 11083854Ammonium dithiocarbamate

Produkt 1

HCID 178470113HCID 178470113, VerbindungAusbeute 65,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Ethyl bromopyruvate (90%, 100 g) was completely dissolved in ethanol (1000 mL), ammonium dithiocarbamate (55.9 g) was added, and the mixture was stirred at room temperature for 2.5 hrs and heated under reflux for 1 hr. After completion of the reaction, the solvent was evaporated under reduced pressure, water was added to the obtained residue. The solid was collected by filtration, washed with water and isopropyl ether, and dried to give the title compound (63.3 g) as a yellow powder.

Aufarbeitung

  1. temperatureheated
  2. temperatureunder reflux for 1 hr
  3. customAfter completion of the reaction
  4. customthe solvent was evaporated under reduced pressure, water
  5. additionwas added to the obtained residue
  6. filtrationThe solid was collected by filtration
  7. washwashed with water and isopropyl ether
  8. customdried

Quellen und Nachweise

ORD-Eintrag
ord-e1e5dc99a7c84d74bd109e9411a8dee4
Quelldatensatz
uspto-grants-2011_05
Patentnummer
US07935700B2

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