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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 545416Erstellt: 26. Oktober 2026

[1,4'-Bipiperidin]-3-ol → (Rac)-(3-hydroxy-[1,4']bipiperidinyl-1'-yl)-[5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3h-imidazol-4-yl]-methanone

https://huagongshe.com/reaction/545416

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt[1,4'-Bipiperidin]-3-olHCID 21091574—
Edukt5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazole-4-carboxylic acidHCID 67133231—
Produkt(Rac)-(3-hydroxy-[1,4']bipiperidinyl-1'-yl)-[5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3h-imidazol-4-yl]-methanoneHCID 57541103—

Reaktionsschritte

In analogy to the procedure described for example 2, 5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazole-4-carboxylic acid (example 36) was coupled with (rac)-[1,4′]bipiperidinyl-3-ol to give the title compound as off-white solid. MS: 563.2 (MH+).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07935707B2
Quelldatensatzuspto-grants-2011_05
ORD IDord-54834fbcda474a9380af99baa2752d52
Quellennotizuspto-grants-2011_05