2-Thiopheneglyoxylic acid → 2-Oxo-3-thiophen-2-yl-1,2-dihydro-quinoxaline-6-carboxylic acid ethyl ester

HRID 548403

Reaktionsgleichung

Reaktionsgleichung von HRID 548403
[CH2:1]([O:3][C:4](=[O:13])[C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[C:7]([NH2:12])[CH:6]=1)[CH3:2].[S:14]1[CH:18]=[CH:17][CH:16]=[C:15]1[C:19](=O)[C:20](O)=[O:21]>>[CH2:1]([O:3][C:4]([C:5]1[CH:6]=[C:7]2[C:8](=[CH:9][CH:10]=1)[NH:11][C:20](=[O:21])[C:19]([C:15]1[S:14][CH:18]=[CH:17][CH:16]=1)=[N:12]2)=[O:13])[CH3:2]

Komponenten

3

Edukt 2

HCID 776942-Thiopheneglyoxylic acidHCID 458855Ethyl 3,4-Diaminobenzoate

Produkt 1

HCID 672070442-Oxo-3-thiophen-2-yl-1,2-dihydro-quinoxaline-6-carboxylic acid ethyl ester

Versuchsvorschrift

The quinoxalin-2-one of the present example is prepared with 3,4-Diamino-benzoic acid ethyl ester and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 2-Oxo-3-thiophen-2-yl-1,2-dihydro-quinoxaline-6-carboxylic acid ethyl ester.

Quellen und Nachweise

ORD-Eintrag
ord-16de8acaf7d34d47a9745002fce7317e
Quelldatensatz
uspto-grants-2011_05
Patentnummer
USRE042375E1

Verknüpfte Notizen

Wird geladen…