4-Nitrophenyl methyl sulfide → (RS)-S-Methyl-S-(4-nitrophenyl)-N-[(5-methyl-2-pyridyl)sulphonyl]sulphimide

Beteiligte Stoffe

Reaktionsschritte

879 mg (2.73 mmol) of iodosobenzene diacetate are added to a suspension of 300 mg (1.77 mmol) of 1-methylsulphanyl-4-nitrobenzene, 610 mg (3.55 mmol) of 5-methyl-2-pyridinesulphonamide, 285 mg (7.10 mmol) of magnesium oxide and 78 mg (0.18 mmol) of rhodium(II) acetate dimer in 12 ml of dichloromethane at room temperature. The mixture is stirred for 24 h and then concentrated. The resulting residue is purified by chromatography (dichloromethane/ethanol 95:5). 326 mg (0.96 mmol; yield: 54%) of the product are obtained.

Herkunft & Nachweise