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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 550060Erstellt: 26. Oktober 2026

2-Pyrimidinemethanol → N-cyclopropyl-4-methyl-3-{[4-(pyrimidin-2-ylmethoxy)benzoyl]amino}benzamide

https://huagongshe.com/reaction/550060

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-PyrimidinemethanolHCID 2763024—
EduktN-cyclopropyl-3-[(4-hydroxybenzoyl)amino]-4-methylbenzamideHCID 66631169—
ProduktN-cyclopropyl-4-methyl-3-{[4-(pyrimidin-2-ylmethoxy)benzoyl]amino}benzamideHCID 1123503558%

Reaktionsschritte

The title compound was prepared from 2-pyrimidinemethanol and N-cyclopropyl-3-[(4-hydroxybenzoyl)amino]-4-methylbenzamide according to the method used to prepared Example 8, to give the title compound as a solid (149 mg, 58%); NMR Spectrum: (DMSOd6) 0.56 (m, 2H), 0.67 (m, 2H), 2.24 (s, 3H), 2.84 (m, 1H), 5.37 (s, 2H), 7.09 (d, 2H), 7.31 (d, 1H), 7.47 (m, 1H), 7.61 (m, 1H), 7.78 (d, 1H), 7.93 (d, 2H), 8.35 (m, 1H), 8.83 (m, 2H), 9.80 (s, 1H); Mass Spectrum: M+H+ 403.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07943776B2
Quelldatensatzuspto-grants-2011_05
ORD IDord-6e303f83664d46d7b2e079308e182710
Quellennotizuspto-grants-2011_05