HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Pyrimidinemethanol → N-cyclopropyl-4-methyl-3-{[4-(pyrimidin-2-ylmethoxy)benzoyl]amino}benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Pyrimidinemethanol | HCID 2763024 | — |
| Edukt | N-cyclopropyl-3-[(4-hydroxybenzoyl)amino]-4-methylbenzamide | HCID 66631169 | — |
| Produkt | N-cyclopropyl-4-methyl-3-{[4-(pyrimidin-2-ylmethoxy)benzoyl]amino}benzamide | HCID 11235035 | 58% |
Reaktionsschritte
The title compound was prepared from 2-pyrimidinemethanol and N-cyclopropyl-3-[(4-hydroxybenzoyl)amino]-4-methylbenzamide according to the method used to prepared Example 8, to give the title compound as a solid (149 mg, 58%); NMR Spectrum: (DMSOd6) 0.56 (m, 2H), 0.67 (m, 2H), 2.24 (s, 3H), 2.84 (m, 1H), 5.37 (s, 2H), 7.09 (d, 2H), 7.31 (d, 1H), 7.47 (m, 1H), 7.61 (m, 1H), 7.78 (d, 1H), 7.93 (d, 2H), 8.35 (m, 1H), 8.83 (m, 2H), 9.80 (s, 1H); Mass Spectrum: M+H+ 403.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07943776B2 |
| Quelldatensatz | uspto-grants-2011_05 |
| ORD ID | ord-6e303f83664d46d7b2e079308e182710 |
| Quellennotiz | uspto-grants-2011_05 |